Allograftic bone marrow-derived mesenchymal stem cells transplanted into heart infarcted model of rabbit to renovate infarcted heart     

王建安  李长岭  樊友启  何红  孙勇 《浙江大学学报(A卷英文版)》2004,5(10):1279-1285

Objective: To investigate the directed transplantation of allograftic bone marrow-derived mesenchymal stem cells (MSCs) in myocardial infarcted (MI) model rabbits. Materials and Methods: Rabbits were divided into 3 groups, heart infarcted model with MSCs transplanted treatment (MSCs group, n=12), heart infarcted model with PBS injection (control group, n=20), sham operation with PBS injection (sham group, n=l 7). MSCs labelled by BrdUrd were injected into the MI area of the MSCs group. The same volume of PBS was injected into the MI area of the control group and sham group. The mortality, LVIDd, LVIDs and LVEF Of the two groups were compared 4 weeks later. Tropomyosin inhibitory component (Tn I) and BrdUrd immunohistochemistry identified the engrafted cells 4 weeks after transplantation. Result: The mortality of the MSCs group was 16.7% (2/12), and remarkably lower than the control group's mortality [35% (7/20) (P＜0.05)].Among the animals that survived for 4 weeks, the LVIDd and LVIDs of the MSCs group after operation were 1.17±0.21 cm and 0.74±0.13 cm, and remarkably lower than those of the model group, which were 1.64±0.14 cm and 1.19±0.12 cm (P＜0.05); the LVEF of the MSCs group after operation was 63±6%, and remarkably higher than that of the model group,which was 53±6% (P＜0.05). Among the 10 cases of animals that survived for 4 weeks in the MSCs group, in 8 cases (80%),the transplanted cells survived in the non MI, MI region and its periphery, and even farther away; part of them differentiated into cardiomyocytes; in 7 cases (70%), the transplanted cells participated in the formation of blood vessel tissue in the MI region. Conclusion: Transplanted allograftic MSCs can survive and differentiate into cardiomyocytes, form the blood vessels in the MI region. MSCs transplantation could improve the heart function after MI.  相似文献   

Usage patterns and social circles on Facebook among elderly people with diverse personality traits     

Fan Mo  Michal Kosinski  David Stillwell 《Educational gerontology》2018,44(4):265-275

Elderly people are exposed to information technologies to keep them in touch with younger generations. Among various technologies, social network sites (SNSs) are seldom used by the majority of elderly people. To bridge the digital divide, it is necessary to dig deeply into the minority elderly users of SNSs. This study explores usage patterns of elderly Facebook users and further investigates how their diverse characteristics influence their usage and social circles. Three findings were derived. First, a sharp digital divide on SNSs does exist, and existing elderly Facebook users are mainly the dabblers. Second, personality profiling could predict elderly people’s SNS usage behaviors. Elderly users with a high level of openness and extroversion have more friends, status updates, and group memberships, and those with a high level of conscientiousness have fewer likes and status updates. Elderly users are likely to seek insightful content on SNSs. Moreover, they may have a higher degree of emotional stability than young users when using SNSs. Third, elderly people tend to build small social circles on SNSs that “copy” the family relationship in the real world; whereas, they build large social circles with interests and hobbies that are difficult to share in the real world. Based on these results, detailed suggestions are presented for better targeting elderly people in ways that move them toward SNSs.  相似文献   

试论开放性管理原则与中国软件企业的管理和发展     

黄璠  欧阳电平 《湖北广播电视大学学报》2001,18(1):54-58

开放性管理原则是指在对企业资源特别是人才和技术资源合理模块化基础上进行结构化配置和管理，以高效简明的接口规范内部的交流和外部扩展；同时，将“可持续性的利润最大化”作为企业管理和发展的始发点和最终决策依据，放开管理和发展的思路，用这种原则指导软件企业的管理和指引发展，实质上就是从软件企业的特点出发分别致力于对内的自我激励和自我约束，以及对外的积极扩充和协调发展，也即内涵的管理和外延的拓展，核心思想就是开放性。  相似文献   

关于文学性以及文学研究问题     

南帆 《江苏理工大学学报(社会科学版)》2005,7(6):56-61

过去的几年里，“文学性”这个概念成为文学研究的一个焦点。其考察大致形成了两个派别的观点，一派被视为本质主义的，例如“纯文学”的概念就是本质主义观点的派生物；一派被视为非本质主义的，认为所谓的本质仅仅是一种幻觉。前者处理的问题较为简单，后者却是将自己置于不尽的问题之流中。与此相关，文学研究的成果是一种知识。知识具有多种形态，科学知识仅仅是一种形态，文学研究以及其他人文学科的研究显示的是另一些知识形态的意义。文学研究时常出现从概念定义出发来衡量具体的文学现象，而文化研究很大程度上就是用具体的分析抵制形而上学的理论趣味。联系后殖民理论来分析中国古代文论的现代转换问题：援引西方的术语范畴可以阐释民族文化的特征，甚至成为反击文化殖民的手段。如果中国古代文论的概念、命题无法企及现今的理论高度，或者远远地游离于现今的历史语境，那么，这种理论就无法承担“现代转换”的使命。  相似文献   

中等职业技术教育与农村人力资源开发     

李月梅  樊保国 《教育与职业》2007,(17):7-9

本文分析了农村人力资源开发的现状与重要性,论述了中等职业技术教育在农村人力资源开发中的地位和作用,提出了发展中等职业技术教育促进农村人力资源开发的措施.  相似文献   

农民主体作用的发挥是社会主义新农村建设的关键     

黄丽萍  林藩 《福建教育学院学报》2007,8(1):28-31

建设社会主义新农村是我国现代化进程中的重大历史任务。建设社会主义新农村的关键在于调动亿万农民的积极性,充分发挥农民在社会主义新农村建设中的主体作用。要充分发挥农民的主体作用,就要以人为本,大力提升农民在社会主义新农村建设中的主体作用,并且按照科学发展观的要求,科学地发挥农民的主体作用。  相似文献   

课程改革进程中教师消极行为研究     

范姣 《教育科学论坛》2005,(12):13-15

教师消极行为的产生是课程改革进程中出现的必然现象。本文试图对新课程改革进程中的教师消极行为作初步简析，揭示教师消极行为的表现特征，找出它的成因，并尝试提出初步的对策思考。  相似文献   

世俗情欲的浪漫升华——新生代女作家的“诗化”小说论     

樊星 《新乡师范高等专科学校学报》2006,20(4):43-47

一部分新生代女作家的“身体写作”具有“诗化”特征。这或诡异、或疯狂的“诗化”风格与古代的“艳诗”在精神上相通,又具有现代派文学集唯美与溢恶于一体的气质。她们对“飞”的感觉的集中渲染让她们的文字也产生了节奏飞快、高速旋转的效果。因此,她们独具特色的“诗化”小说丰富了我们对于“诗化小说”这一文体的理解。  相似文献   

引导聋生快乐学习数学的策略刍探     

范丽龄 《成才之路》2020,(1):82-83

对于聋生而言,快乐学习是走向成功的重要途径。要做到这一点,教师就要注重培养聋生的数学兴趣,教给聋生养成良好习惯的方法,培养聋生的数学阅读能力,让聋生在快乐的氛围中学习数学,提高适应社会的能力。  相似文献   

高效率音频放大器的研究     

范广忠  吴洪哲等 《鸡西大学学报》2002,2(2):44-45

论述了提高音频放大器效率的方法，介绍了D类放大器的电路组成，输出采用全桥式双极输出，采用占空比在0－100％可调的PWM信号进行控制使效率得到大幅度的提高。  相似文献